赵梦瑶
食品科学与工程专业：硕士生导师
生物与医药专业（生物工程领域）：硕士生导师
个人介绍：
赵梦瑶，博士，特聘副研究员，2018年入选上海市“浦江人才”A类计划。博士毕业于中国农业大学食品科学与工程专业，博士期间于加拿大渥太华大学食品安全与毒理学系联合培养两年，于毕业同年入职。
研究方向：
主要致力于食品营养与安全领域的研究，包括食品功能因子的生理活性评价、食源性热加工有害物毒理及安全性评价等。在该领域发表研究论文40余篇（SCI论文30余篇，JCR Q1 17 篇），其中以第一作者或通讯作者在Food Chem., J. Agric. Food Chem., Pharmacological Res., Food Funct., Carbohyd. Polym.等SCI期刊发表论文18篇。
主持或参加的科研项目或基金：
近年来主持多项包括国家自然科学基金青年基金、上海市浦江人才计划、国家重点研发计划子课题等在内的多个省部级项目、人才计划。
1. 国家自然科学基金青年基金（31801668），“食源性有害物丙烯酰胺通过NLRP3炎症小体激活介导神经毒性的机制探索”，2019-2021，主持；
2. 上海市浦江人才计划A类（18PJ1401900），“NLRP3炎症小体介导的细胞焦亡在食源性有害物丙烯酰胺神经致毒中的机制研究”，2018-2020，主持；
3. 国家重点研发计划子课题，“水产品智能化加工装备与关键技术”，2019-2022，子课题主持；
4. 中国博士后科学基金特别资助（2019T120314），“单一聚合度壳寡糖对非酒精性脂肪肝的干预效果及机制研究”，2019-2021，主持；
5. 中国博士后科学基金面上资助（2017M621392），“单一聚合度壳寡糖促体内外肝癌细胞凋亡机制研究”，2017-2019，主持；
教学：
本科生：专业必修课《食品工艺学》（48学时）、《食品环境学》。
研究生：专业选修课《分子营养与免疫》
代表性论文（*通讯作者）：
1. Mengyao Zhao, Shumin Chen, Xiaoguo Ji, Xin Shen, Jiangshan You, Xinyi Liang, Hao Yin*, Liming Zhao*. Nutraceuticals and functional foods for intervention of non-alcoholic fatty liver disease, Pharmacol. Res., 2021, 166, 105517.
2. Mengyao Zhao, Linlin Deng, Xiaoxuan Lu, Liqiang Fan, Yang Zhu, Liming Zhao*. The involvement of oxidative stress, neuronal lesions, neurotransmission impairment, and neuroinflammation in acrylamide-induced neurotoxicity in C57/BL6 mice. Environ. Sci. Pollut. Res., 2022, doi.org/10.1007/s11356-021-18146-2.
3. Linlin Deng, Mengyao Zhao*, Yanan Cui, Quanming Xia, Lihua Jiang, Hao Yin & Liming Zhao*. Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells, Drug Chem. Toxicol., 2021, DOI: 10.1080/01480545.2021.1979030.
4. Xin Shen, Xinyi Liang, Xiaoguo Ji, Jiangshan You, Xinye Zhuang, Yudong Song, Hao Yin, Mengyao Zhao* and Liming Zhao*. CD36 and DGAT2 facilitate the lipid-loweringeffect of chitooligosaccharides via fatty acidintake and triglyceride synthesis signaling. Food Funct., 2021, 12, 8681-8693.
5. Chunfeng Zhu, Mengyao Zhao*, Liqiang Fan, Xuni Cao, Quanming Xia, Jiachun Zhou, Hao Yinand Liming Zhao*.Chitopentaose inhibits hepatocellularcarcinoma by inducing mitochondrialmediated apoptosis and suppressing protectiveautophagy. Bioresources and Bioprocessing. 2021, 8:4.
6. Mengyao Zhao, Xin Shen, Xiaodan Li, Baoli Chen, Liqiang Fan, Quanming Xia, Liming Zhao*. Chitooligosaccharide supplementation prevents the development of high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in mice via the inhibition of cluster of differentiation 36 (CD36). J. Funct. Foods. 2019, 57, 7-18.
7. Mengyao Zhao, Liming Gu, Yun Li, Shumin Chen, Jiangshan You, Liqiang Fan, Yudong Wang, Liming Zhao*. Chitooligosaccharides display anti-tumor effects against human cervical cancer cells via the apoptotic and autophagic pathways. Carbohyd. Polym. 2019, 224, 115171.
8. Mengyao Zhao, Li Dong, Chunfeng Zhu, Xiaosong Hu, Liming Zhao, Fang Chen*, Hing Man Chan*. Proteomic profiling of primary astrocytes and co-cultured astrocytes/microglia exposed to acrylamide. Neruotoxicology, 2019, 75, 78-88.
9. Xiaodan Li#, Mengyao Zhao#, (co-first author) Liqiang Fan, Xuni Cao, Liehuan Chen, Y. Martin Lo, Liming Zhao*. Chitobiose alleviates oleic acid-induced lipid accumulation by decreasing fatty acid uptake and triglyceride synthesis in HepG2 cells. J. Funct. Foods. 2018, 46, 202-211.
10.Mengyao Zhao, Fu Sheng Lewis Wang, XiaoSong Hu, Fang Chen*, Hing Man Chan*. Acrylamide induced neurotoxicity in primary astrocytes and microglia: roles of the Nrf2-ARE and NF-<kappa>B pathways. Food Chem. Toxicol. 2017.
11. Mengyao Zhao, Pengpu Wang, Daotong Li, Xiaosong Hu, Fang Chen*. Protection against neo-formed contaminants (NFCs)-induced toxicity by phytochemicals. Food Chem. Toxicol. 2017.
12. Mengyao Zhao, Fu Sheng Lewis Wang, XiaoSong Hu, Fang Chen*, Hing Man Chan*.Effect of acrylamide-induced neurotoxicity in a primary astrocytes/microglial co-culture model.Toxicol. in Vitro. 2017.
13. Mengyao Zhao,Pengpu Wang, Daotong Li, Xiaosong Hu, Fang Chen*. The chemoprotection of a blueberry anthocyanin extract against the acrylamide-induced oxidative stress in mitochondria: unequivocal evidence in mice liver. Food Funct. 2015.
14. Mengyao Zhao,Pengpu Wang, Xin Liu, Xiaosong Hu, Fang Chen*. Blueberry anthocyanins extract inhibits acrylamide-induced diverse toxicity in mice by preventing oxidative stress and cytochrome P450 2E1 activation. J Funct. Food. 2015.
参编专著、教材：
1. Mengyao Zhao, Liming Zhao*. Chater 8. Biological activities and potential application in food industry. In BookOligosaccharide of Chitin and Chitosan: Bio-manufacture and applications. Publisher: Springer Nature. 2019. 9. ISBN 978-981-13-9401-0
2. 赵黎明，赵梦瑶。译《第十五章》，《食品分析（第五版）》（国外优秀食品科学与工程专业教材）；中国轻工业出版社。ISBN 978-7-5184-2138-1。
主要学术、社会兼职
上海市食品学会青年工作委员会 副秘书长
联系方式：
办公室：实验5楼109
电话：021-64251881
通讯地址：上海市徐汇区梅陇路130号3044am永利集团官网，200237
Email: myzhao@ecust.edu.cn.